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The use of mitochondrial transplantation therapy, an innovative approach, has also advanced to human clinical trials

TH-2-31 (N 2 ,N 3 -dicyclohexyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridine-2,3-diamine) was synthesized by Curia

The most popular model is to transplant human cancer cells into the mice, to form visible nodules, and to test the effects of drugs on the nodule sizes

We are cognizant of some limitations of the present study

(A) Expression of the glutathione reductase-encoding gene GTR1 in WT strains was induced more than two-fold in the presence of 5 mM H2O2 compared to CM alone