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Furthermore, some inflammatory markers, like tumor necrosis factor-alpha (TNF-), cyclooxygenase-2 (COX-2), and interleukins (IL), can induce the expression of antioxidant enzymes as part of the cellular response to inflammation [16]

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196,198 Moreover, in vitro chemoattractants, such as CXCL8, can act as chemorepellents at higher concentrations, 199 which allows for possible changes in neutrophil behavior as cells migrate along chemokine gradients

Oral glutathione supplements are not effective because the benefits are lost during the digestion process