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The active ingredient, semaglutide, was approved by the FDA in 2021 for chronic weight management in adults and children 12 and older with obesity and for adults who are overweight with one or more weight-related health conditions, like type 2 diabetes or high blood pressure

As a part of the immune system, it has a protective role for infections, and it is a double-edged sword in the brain (157)

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Recently identified melanoma stem cell markers include JARID1B (jumonji, AT-rich interactive domain 1B), ABCB5 (ATP-binding cassette subfamily B (MDR/TAP) member 5), ABCG2 (ATP-binding cassette subfamily G member 2), and MDR1 (multi-drug resistance 1) [27]