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Like most skincare actives, GHK-Cu works gradually with regular use rather than overnight

And when combined with acetyl hexapeptide-8 as in Argirelox it can be used to extend the anti-wrinkle effects of Botox injections.32 Syn-Ake In a recent 2024 study examining in silico and in vitro tests, Syn-Ake displayed antioxidant capabilities, meaning it could help scavenge free radicals and prevent them from damaging or aging skin.33 Additionally, a 2024 review explained that the peptide may prevent the uptake of sodium ions in muscles, keeping them relaxed and reducing the risk of developing wrinkles

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Gene expression studies revealed that GHK-Cu modulates over 4,000 human genes, with 50% moving toward patterns seen in younger, healthier individuals