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Moreover, METTL3 protein levels were inversely correlated with the levels of ferroptosis modulators SLC7A11 and FSP1 in human aortas

Oxidative stress as a driver of reduced fertility with age Social and economic changes are leading women to increasingly postpone motherhood, and as a result, the proportions of pregnancies at advanced maternal age (AMA), commonly defined as 35 years, continue to rise [7,8,9]

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Methionine adenosyltransferases 2A (MAT2A), the key enzyme for methionine metabolism, catalyzes the biosynthesis of SAM from methionine and expresses in various tissues (Figs