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10.1097/00007632-200212010-00007 141 KudelkoM.ChenP.TamV.ZhangY.KongO.-Y.SharmaR.et al (2021)

How long it lasts can be anywhere from a few minutes to hours, based on the dose and how well the patient can handle it

Also, hydroxocobalamin binds the gas nitric oxide, which is part of inflammation and increases blood flow during inflammation especially important in migraine

Am J Physiol - Cell Physiol (1987) 253:C85461

Bioconjugation: The compound plays a significant role in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the efficacy of drug delivery systems