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doi: 10.3390/biom12030360 47

The depletion of GSH, achieved in clinics with the specific GSH synthesis inhibitor buthionine sulphoxymine (BSO), is an important strategy to improve drug efficacy in anticancer therapies, since many aggressive tumor cells are very efficient in drug extrusion (multi-drug resistant, MDR), thereby nullifying the effects of chemotherapies

The side chain protecting group remains intact during coupling and is not split off during the deprotection of the amino-terminus protecting group or during coupling

Yet while he adapts to so much change around himas so many have throughout the Mass General communityStilwell has felt the pandemic hit his close-knit team directly