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Results TMAO activates quiescent, but not conventionally cultured, valve interstitial cells First, we sought to test the hypothesis that TMAO triggers VIC activation using primary female porcine VICs grown in standard culture

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Indeed, by comparing the single blastomere transcriptomic profiles of bovine in vivo and in vitro derived blastocyst, a recent study has shown that there are highly active metabolic and biosynthetic processes, reduced cellular signaling, and reduced transmembrane transport activities in IVP embryos that may lead to reduced developmental potential [59]

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