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It is reasonable to assume that changes in CpG methylation levels in this region may reflect on the epigenetic landscape, possibly favoring the expression of CCL11

Since reticulocytes are nascent immature RBCs which are yet to undergo enzymatic glycation, the HbA1c values can be spuriously low in cases where there is spurt in erythropoiesis like this case where the Vit B12 deficiency was met by supplementation