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Model analysis Selection of parameters for estimation The methodology to select parameters for estimation involves first conducting local sensitivity analysis (LSA) to obtain a set of important parameters, and then determining from this set of parameters which are identifiable, that is for which parameters a value can be identified from the data, taking into account the model structure

Following a dose of radiolabeled pregabalin, approximately 90% of the administered dose was recovered in the urine as unchanged pregabalin

Whole blood Cytosolic whole blood GSSP: lyse 0.2 ml of whole blood by addition of three volumes of water

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