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It was previously believed that Accutane caused an increase in depression, psychosis, and suicidal thoughts, but according to studies published in the Journal of American Dermatology in 2017 and the British Medical Journal in 2019, there is no evidence to suggest that Accutane causes an increase in these mental health problems

Several studies have reported that selective serotonin reuptake inhibitors (SSRIs) can lead to drug-induced alopecia 36,37

Some practitioners have considered it for the management of neuropathic pain, as well as in the adjunctive treatment of certain psychiatric conditions where vitamin B12 plays a supportive role in managing symptoms

The peptide complex restores extracellular matrix homeostasis by increasing the synthesis and turnover of collagen, elastin, and glycosaminoglycans, as well as by modulating the balance between metalloproteinases (MMPs) and their inhibitors (TIMPs), thus supporting both matrix remodeling and scar resolution 2,3

Observational findings suggest that BPC 157 may support fibroblast outgrowth and cellular organization associated with tendon tissue repair