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Thioredoxin, itself, is a transcription factor that has been shown to induce MnSOD [34]

Additionally, NRC-03 and NRC-07, two AMPs from the pleurocidins AMP family, exhibited equal killing effect at a concentration of 50M on normal MCF7 cells and on paclitaxel-resistant breast cancer cell line MCF7-TX400 that possess 2.6 times of P-gp expression more than the normal MCF7 cells, achieving about 60% of cell killing rate

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doi: 10.1073/pnas.1607571113 29 VermeulenRCWKurkRMVisserFCSluiterWScholteHR