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Mechanism of formation of the Maillard protein cross-link pentosidine Glucose, fructose, and ascorbate as pentosidine precursors

Malignant phenotype of tumor cells is caused by the Ras gene, often mutated or active in tumor cells, and leads to aberrant tumor cell proliferation, programmed cell death, invasion and angiogenesis (42)

It can also improve the chemoresistance of tumor cells by increasing the sensitivity of ovarian tumor cells to ferroptosis and guide clinical decision-making by analyzing the tumor risk prognostic model of ferroptosis-related genes in ovarian tumor tissues

Interestingly, apoE2 and apoE3 cleared more A than apoE4 in transgenic mice (Dodart et al., 2005

In recurrent or metastatic disease, remodeling of the tumor immune microenvironment may potentially expand the population of patients who might benefit from immune checkpoint blockade