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Research shows that MOTS-c activates the AMPK pathway, which regulates cellular energy balance and helps restore metabolic stability under stress conditions

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TAMs adjust their activation state, synthesis of inflammatory cytokines, and proliferation of peroxisomes by modulating glutamine metabolism [123]

Lin C-C, Hsiao L-D, Cho R-L, Yang C-M (2019) Carbon monoxide releasing molecule-2-upregulated ROS-dependent heme oxygenase-1 axis suppresses lipopolysaccharide-induced airway inflammation