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According to a peer-reviewed study published in PLOS ONE confirming that Semax affects the expression of genes related to the neurotrophin signaling pathway, specifically upregulating BDNF in the hippocampus, Semax significantly increases BDNF and its receptor TrkB in the rat hippocampus, with effects on both memory and neuronal resilience

Severe injection site reactions : Mild soreness is normal, but increasing pain, significant swelling, or signs of infection (redness, warmth, discharge) require medical review

Clinical support options such as injections or nasal sprays may raise levels more effectively, but human studies on beauty outcomes remain limited

Epidural steroid injections are relatively safe and minimally invasive

Zang WW, Zhu LP, Wu HS