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Incidence of stroke according to presence of diabetic nephropathy and severe diabetic retinopathy in patients with type 1 diabetes

Large, buoyant LDL is generally considered non-pathogenic

69 Although MCT2 mediates neuronal lactate uptake, its inhibition reduces pathological lactylation but also diminishes lactate-induced synaptic protein expression (eg, PSD95, GAP43), ultimately impairing memory consolidation

reported side effects include: headache hypertension Drug Interactions: may cause hypertension if given with other pressor agents References: Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)

Should single outlying INRs occur during routine monitoring, a repeat INR should be conducted within 1 to 2 weeks to confirm whether dosage adjustments are clinically necessary