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Firstly, the absence of similar pathways in mammals may reduce the toxicity of related drugs

doi: 10.1242/jcs.115.15.3193 258 LieberthalWLevineJS

doi: 10.1016/j.jaci.2009.12.980 31 ChaudharyA.MillerS

Nevertheless, the association among mitochondrial dysfunction, intracellular or mitochondrial calcium concentration, and the stone pathogenesis remains unclear and should be further elucidated