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[333] found in the brains of Fmr1 -knockout (KO) mice elevated levels of ROS, GSH, markers of protein oxidation and lipid peroxidation in whole brains, and increased production of NADPH oxidase in the prefrontal cortex, cerebellum, and hippocampus

64 : 12871292 Nishinaka Y, Masutani H, Oka S, Matsuo Y, Yamaguchi Y, Nishio K, Ishii Y and Yodoi J (2004) Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1

Beyond providing mechanical support, this unit regulates solute exchange that influences cartilage nutrition and metabolism

After 2 freeze-thaw cycles, 5% 5-sulfosalicylic acid (SSA, 20 L) was added, and the samples were centrifuged at 8000 g for 10 minutes at 4C