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Heart, liver, kidney and brain tissues were rapidly removed and clamped frozen at liquid N 2 temperature and stored at80 C

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Dosing should be individualized and titrated according to clinical response, typically starting at 30 mg three times daily and increasing in 30 mg increments every 23 days to a target range of 60120 mg per dose every 36 hours

Mechanism of action DNF-10: decreasing food intake It has been demonstrated that there is a significant impact on the modulators of short-term food intake at both the hypothalamic level (NPY) and the digestive level, resulting in a decrease in the hunger hormone ghrelin

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