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Front Physiol 11: Tylutka A, Walas , Zembron-Lacny A (2024) Level of IL-6, TNF, and IL-1 and age-related diseases: a systematic review and meta-analysis

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Our studies to date suggest that during reperfusion the enolate nucleophile of 2-ACP limits the consequences of mitochondrial-based oxidative stress through scavenging unsaturated aldehyde electrophiles (e.g., acrolein) and chelation of metal ions that catalyze the free radical generating Fenton reaction

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10.1126/scitranslmed.abn3464 201 RichnerJ

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The significance of Chimeric Antigen Receptor-T (CAR-T) cell therapy lies in its ability to enhance and equip the patients own T cells ex vivo to more effectively target tumor-associated antigens, thus rejuvenating weakened immune environments [168]

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2) Lowers Inflammation Glutathione (GSH) blocks the production of most inflammatory cytokines

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