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Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation

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This aligns with evidence that mitochondrial fission can proceed without changes in DRP1 expression, such as with deletion of PTEN-induced kinase 1 or protein kinase A activation, which affect DRP1 phosphorylation at Ser616 without altering protein levels [61, 62]