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ZIP14-knockout mice develop dwarfism, osteopenia, impaired skeletal growth, ER stress, metabolic abnormalities and manganese overload, illustrating the broad physiological impact of endosomal metal transport 173,174

Journal of endourology / Endourological Society

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Specifically, combining LNPs with viral vectors carrying promoterless DNA templates enables concurrent delivery of ZFNs [338]

In astrocytes, APOE4 increased de novo cholesterol synthesis despite intracellular cholesterol accumulation caused by lysosomal sequestration