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10.1038/s41398-019-0456-z Transl
26 Through mediating the post-translational modification dependent on NAD + , sirtuins modulate the adaptation to the altered cellular energetic status, especially the activation of oxidative metabolism and stress resistance in mitochondria in various physiological or pathological conditions
Demonstrated that administration of NMN, an NAD + precursor, markedly reduced subcutaneous fat mass in mice fed a high-fat diet (HFD)
Cold exposure can stress the cardiovascular system, particularly in individuals with coronary artery disease
