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In older people, a B12 deficiency usually happens as a result of insufficient levels of either stomach acid or intrinsic factor that limit absorption

There isnt a single correct answer that applies to everyone

In the study by Neelakantan et al

The short answerit can vary by individual, but many people begin feeling noticeable effects within hours or days

Studies show the consuming an excessive amount of vitamin B12 may: Increase the risk of cardiovascular events in people with diabetic nephropathy : A study published in JAMA sought to determine whether B vitamin therapy was able to slow the progression of diabetic nephropathy (kidney damage due to diabetes) and prevent vascular complications