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mainly Japan with an incidence rate of 1:69 and 1:65 in China [135, 136]

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9 Standards need to be developed for clinical applications Over the past few decades, research and therapy based on mesenchymal stem cells (MSCs) have made significant progress due to their advantages such as immune evasion capability, diversity of source tissues, ease of isolation, rapid expansion, and tissue repair and immunomodulatory functions

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