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All mice were raised and maintained under specific pathogen-free (SPF) or germ-free (GF) conditions

J Clin Invest 101:21012111

In a recent example, Wang et al

Methionine then undergoes a process called the one-carbon cycle to produce S-adenosyl-l-methionine (SAMe), a major methyl donor which plays an essential role in producing neurotransmitters