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In preclinical work, Dihexa promoted dendritic spine formation at concentrations reported to be far more potent than BDNF on a molar basis in specific assays [McCoy et al., 2013]

Storing the compound in a desiccated and temperature-controlled environment helps maintain its integrity for precise chemical synthesis

Gewirtz, Targeting tumor cell senescence and polyploidy as potential therapeutic strategies

The principle is true to a large extent as ionised drugs have low lipid solubility and relatively poor permeability

Some animal studies have indicated potential benefits in wound healing and tissue repair, though these findings have not been replicated in rigorous human clinical trials