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In addition to a potentially direct antioxidant activity, curcumin can induce the expression of phase II antioxidant enzymes, including glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione synthesis

However, none of these models capture the full spectrum of AD molecular events and pathologies as they exhibit less severe neurodegeneration compared to human patients

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For viral transduction, the thawed virus was added to HEK293T plated the day prior

Abstract Many cellular signaling pathways contribute to the regulation of cell proliferation, division, motility, and apoptosis