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It is worth noting that these pre-clinical studies were conducted in mice, whose tumor lymphatic drainage and lymphosome are distinct from those of humans

Because multiple lipomas are often linked with mutations in tumor suppressor genes, FML can be considered clinically to be a marker for the presence of an underlying tumor suppression gene mutation and affected patients and their families should be appropriately screened

Funding This work was supported by General Program of Wuxi Commission of Health (M202225), General Projects of Wuxi Medical Center, Nanjing Medical University (WMCG202405)