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10.1093/eurjhf/hfs105 Eur J Heart Fail

one in the field of chemistry and the other a Nobel peace prize

Interventions aimed directly at increasing sGC activity independently of its redox state (also known as sGC agonists, namely sGC stimulators and sGC activators) could show therapeutic potential under those circumstances

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However, until such interventions become available, alternative pharmacological approaches must be explored, considering their associated risks