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3.7 Chondroprotective effects of Se/LDH@PEG-M-modulated macrophage polarization Macrophages M1 polarization in synovial tissues plays a significant role in cartilage degeneration [56]

In the human study M1 was also observed, contributing 7.8% of total circulating radioactivity

Studies have shown that the absence of kisspeptin signaling in rodents and humans can lead to hypogonadotropic hypogonadism (HH) and difficulty in sexual maturation [2]