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We determined an optimal celastrol dose of 1 mg/kg/day in vivo for DKD mice and that celastrol exhibited efficacy comparable to losartan potassium in treating db/db mice

Limitations Participants in our study were treated with various antipsychotics

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Nicotinamide riboside Chloride reduces cognitive deterioration in a transgenic mouse model of Alzheimers disease [2]

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