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doi:10.1007/BF00805158

In controlled laboratory conditions, it may be included in experimental studies examining peptide stability, structural characteristics, and molecular interaction behavior

(ref) Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JS

10 ul of each drug solution was added to 90 ul of the rat blood serum samples and at specific time intervals the researchers terminated metabolism by adding 1 ml of ACN and acetic acid in order to precipitate the proteins which were then removed after overnight refrigeration followed by centrifugation