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Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide Attenuates Cigarette Smoke-Induced Emphysema and Cardiac Dysfunction in Mice

Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75NGFR, TrkA, TrkB, and TrkC) in the adult human peripheral nervous system and nonneural tissues

Yeah, it was Mercury

In phase I trial, four dose levels of TCP (20 mg, 40 mg, 60 mg, 80 mg on days 128) were examined in combination with fixed dose of ATRA (45 mg/m 2 on days 1028) and fixed-dose of AraC (40 mg on days 110) to determine the dose used in phase II clinical trial, and then phase II trial was designed to evaluate the efficacy of TCP at recommended dose in patients with AML or MDS

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