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Acknowledgements This work was supported by project number 2020/39/B/NZ9/01894 from the National Science Centre (NCN), Poland and by the project number WZ/WB-II/2/2023 from the Ministry of Science and Higher Education.The authors are very grateful to Professor Shimshon Belkin, Dr Tal Elad, Dr Liat Moscovici and Dr Sharon Yagur-Kroll, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel for providing bacteria strains

Most of the time, the tissues replenish themselves with water from food and beverages

A conservative approach: if BPC-157 is initiated in a patient on a stable SNRI regimen, do not simultaneously adjust the SNRI dose

Best choice: NAC for acute lung and mucus-related issues

coli and Clostridium perfringens , both of which are known to disrupt TJ proteins and increase epithelial permeability [84, 85]