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Most of the ingredients break down gradually, becoming less effective

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64,144,145 Several other SNPs in genes such as TNF-related apoptosis-inducing ligand (TRAIL), 68 Interleukin-6, 42,43 Signal Transducer and Activator of Transcription 3 (STAT3), 62 Adiponectin, 25 Leptin receptor, 45 peroxisome proliferator-activated receptor-alpha (PPAR), 58 PPAR, 59 peroxisome proliferator-activated receptor gamma-coactivator 1 alpha (PGC-1) 57 have also been correlated with the NAFLD disease progression (Table 1)

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The supernatant was collected for the estimation of the protein by Bradford method, superoxide dismutase (SOD), 21 protocol, estimation of catalase activity 22 , glutathione peroxidase (GPx) level 23 , malondialdehyde (MDA) content 24,25

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Pickart L, Vasquez-Soltero JM, Margolina A (2015)

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