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L'enzyme slnie glutathion-peroxydase est essentielle la dtoxication des oxydants de type peroxydes (eau oxygne, peroxynitrite), qu'ils soient d'origine exogne ou endogne (respiration cellulaire, peroxyde d'hydrogne form par d'autres processus antioxydants complmentaires, peroxynitrite impliqu dans l'apoptose cellulaire ou le systme immunitaire)

Sekwencja to Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val (zapis jednoliterowy: GEPPPGKPADDAGLV )

PS2-modified siRNA has demonstrated improved stability and efficacy compared to unmodified siRNA and has been effective in preclinical models of cancer and viral infections [67]