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The study used 36 male Sprague-Dawley rat pup, exposed to 250 mg/kg PPA to induce ASD-lke features, and pre-treated for 27 days with either yogurt, artichoke extract (400 mg/kg), luteolin (50 mg/kg) or Lacticaseibacillus rhamnosus GG (0.2 mL/day)

Elevated Lipoprotein(a) and Risk of Aortic Valve Stenosis in the General Population. Journal of the American College of Cardiology, vol

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Weight of evidence: Overall evidence is Low-Moderate: multiple animal studies and a growing number of small clinical trials suggest benefits across gutbrain signaling, social and behavioral domains, gastrointestinal symptoms, and neurophysiological patterns, yet most human studies rely on caregiver-reported outcomes, lack biomarker integration, and seldom control for diet, comorbidities, or baseline microbiome composition