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What they found: Oral AOD-9604 reduced body fat by 18 to 22 % vs placebo, comparable to injection administration No changes in total body weight (because lean mass rose slightly) Decrease in plasma triglycerides by 30 % Decrease in resting free fatty acids (paradoxically, mobilization of fat from depots into oxidation) No GI side effects Why it matters: It suggested that AOD-9604 could work orally , a rare property for a peptide

The trial did not demonstrate significant weight loss compared to placebo

A: AOD-9604 includes an additional tyrosine (Tyr) residue at the N-terminus, making it technically Tyr-hGH Fragment 177-191

Copper peptides, particularly GHK-Cu (Glycyl-Histidyl-Lysine), have been studied for their potential benefits in addressing hair loss

additionally, more research is required to investigate differences between NAD + modulators within different tissues, different models or pathologies, administration or exercise regimens, and how to successfully translate these findings to humans, while several clinical trials have already been conducted