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In a recent study, Michigan State University researchers screened key waters in Michigan using alternative indicators and actual pathogen monitoring, and the results demonstrate the range of information that can be obtained through alternative testing methods

These aren't subtle once you know what to look for, but they develop gradually enough that many people adapt without connecting them to a nutrient gap

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However, the low serum B12 levels may not reflect true B12 deficiency in view of the finding in animal studies that metformin increases liver accumulation of vitamin B12 (Greibe et al., 2013

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