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The strongest human evidence is for the intranasal route : small Russian clinical trials in generalized anxiety and neurasthenia reported anxiolytic effects comparable to medazepam , but without the sedation or dependence typical of benzodiazepines [1] [2]

Expert Opinion refers to a statement, achieved by consensus of the Panel, that is based on Panel members clinical training, experience, knowledge, and judgment for which there is no evidence

Hence, the use of such drugs may have a multisystem effect and lead to the development of chronic illnesses such as ME/CFS

Examples of beta-2 agonists are: bambuterol, formoterol, salbutamol, and salmeterol

Meharena, H