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Treatment with zoledronate increased the expression of RhoA, which could not be rescued by GGPP co-incubation (Figure 3d)

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Under normoxic conditions, HIF- is hydroxylated by the EGLN (EGL nine homolog) family, also referred to as prolyl hydroxylase domain-containing proteins (PHDs), and subsequently targeted for degradation

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Similar content being viewed by others Introduction Ionizing radiation exposure may not only cause acute radiation syndrome, but there is also an increased risk of late effects