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40 Gene therapies to relieve PD symptoms have recently reached clinical trials evaluating the efficacy and safety of delivering vectors with genes encoding for overexpression of (1) glutamic acid decarboxylase in the subthalamic nuclei to increase the GABA basal tone, 41,42 (2) enzymes to increase endogenous striatal dopamine synthesis or conversion of l-dopa to dopamine, 43 and (3) neurturina ligand similar to glial cell line-derived neurotrophic factor (GDNF) that has been shown to enhance survival and outgrowth of dopaminergic neurons

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For this reason, radioprotectants may still be beneficial

Ein niedriges GSH in Monozyten zeugt somit von einem primren Mangel an Cystein oder (selten) einem GSH-Synthesedefekt