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Short-term use for specific occasions appears safe, but long-term daily use in men requires careful consideration and medical supervision

doi: 10.1016/j.fertnstert.2004.11.022 112 MeseguerMMartinez-ConejeroJOConnorJEPellicerARemohJGarridoN

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Treatment of Osteoporosis in Postmenopausal Women The safety of Reclast in the treatment of postmenopausal osteoporosis was assessed in Study 1, a large, randomized, double-blind, placebo-controlled, multinational study of 7736 postmenopausal women aged 65 to 89 years with osteoporosis, diagnosed by BMD or the presence of a prevalent vertebral fracture