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DOI: 10.1016/j.jchromb.2011.09.039 74

Huser, W., Walitt, B., Fitzcharles, M.-A

Theoretically, it can be assumed that the highrisk schizophrenia genes would affect the AKTGSK3 signaling pathway, and thus cause NMDA receptor dysfunction, leading to aberrant neuronal systems that are responsible for the positive, negative, and cognitive symptoms observed in schizophrenia