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There is limited clinical data published on intrathecal iron chelation in neurodegeneration, and no iron chelator is officially approved for IT use, given that this is a rather invasive experimental approach

In addition, the ALT and AST levels in OXA and GSH-treated mice did not recover to within the normal range, indicating that GSH alone is insufficient for suppressing oxidative stress during OXA-induced ALI

All patients aged 18 years, positive for hepatitis B surface antigen (HBsAg) and antibodies to HDV (anti-HD), were considered eligible

Lancet 382 , 17651767 (2013)