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Cardiac fibroblasts: friend or foe

Meanwhile, cytokines including TNF-, IL-1, IFN-, and IL-6 could promote the activation of XO, resulting in the production of ROS (73)

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It was further shown that OTUB1, CD44v, and SLC7A11 form a trimeric complex and that CD44v promotes SLC7A11 protein stability by maintaining the interaction between OTUB1 and SLC7A11