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Damaged cytosine products resulting from inflammation, particularly halogenated cytosine residues, are likely to facilitate binding with methyl-binding proteins and enzymatic methylation (101)

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Nuclear translocation of NE and MPO drives chromatin decondensation, NETs are released extracellularly, and platelets and NETs together promote coagulation and thrombosis

Its also the single most protective antioxidant produced by the body and is therefore the most important for protecting cells against oxidative stress from dietary and environmental free radicals as well as those resulting from normal metabolic processes