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The cardioprotective effect of dietary antioxidants on cardiovascular health is a well-established fact based on various studies

However, like previous studies, researchers attributed the cytotoxicity of elesclomol to the excessive production of ROS and could not explain why the cell death induced by elesclomol was closely related to mitochondrial respiration and why the sensitivity of cells with active mitochondrial respiration to elesclomol was nearly 1000 times higher than that of cells with active glycolysis

The authors inferred that reduced glucagon secretion may have played a role

This factor is essential for the absorption of vitamin B12 in the stomach

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