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10.1016/j.ajhg.2019.09.006 420 ZhaoX.HuS.WangL.ZhangQ.ZhuX.ZhaoH.et al (2014)

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CO-STIMULATION Receptor-mediated signals required in addition to antigen-receptor engagement to achieve complete lymphocyte activation

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They need to be, because only a small amount of drug is delivered to each cancer cell by the antibody

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12 Potential adverse effects and risk considerations of probiotic supplementation 12.1 Historical safety record and regulatory frameworks For centuries, the consumption of fermented foods containing live microorganisms has been associated with human health benefits, providing a strong historical foundation for their safety

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